node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A05_orf129 | ftsY | MPN_423 | MPN_425 | Conserved hypothetical protein; MPN423(new), 417(Himmelreich et al., 1996). | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.779 |
A05_orf129 | glpQ | MPN_423 | MPN_420 | Conserved hypothetical protein; MPN423(new), 417(Himmelreich et al., 1996). | Glycerophosphoryl diester phosphodiesterase; MPN420(new), 420(Himmelreich et al., 1996); To glycerophosphoryl diester phosphodiesterases (EC 3.1.4.46). | 0.508 |
A05_orf129 | mnmA | MPN_423 | MPN_422 | Conserved hypothetical protein; MPN423(new), 417(Himmelreich et al., 1996). | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.773 |
A05_orf129 | smc | MPN_423 | MPN_426 | Conserved hypothetical protein; MPN423(new), 417(Himmelreich et al., 1996). | SMC family, chromosome/DNA binding/protecting functions; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.779 |
A05_orf129 | yidA-3 | MPN_423 | MPN_427 | Conserved hypothetical protein; MPN423(new), 417(Himmelreich et al., 1996). | Hydrolase/phosphatase; MPN427(new), 413(Himmelreich et al., 1996). | 0.540 |
A05_orf129 | ylxM | MPN_423 | MPN_424 | Conserved hypothetical protein; MPN423(new), 417(Himmelreich et al., 1996). | Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein (By similarity). | 0.779 |
F10_orf158 | K04_orf222 | MPN_329 | MPN_239 | Ferric uptake regulator; MPN329(new), 508(Himmelreich et al., 1996); Koonin for MG homolog. | Conserved hypothetical protein; MPN239(new), 593(Himmelreich et al., 1996). | 0.615 |
F10_orf158 | whiA | MPN_329 | MPN_241 | Ferric uptake regulator; MPN329(new), 508(Himmelreich et al., 1996); Koonin for MG homolog. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.607 |
F10_orf158 | ylxM | MPN_329 | MPN_424 | Ferric uptake regulator; MPN329(new), 508(Himmelreich et al., 1996); Koonin for MG homolog. | Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein (By similarity). | 0.590 |
K04_orf222 | F10_orf158 | MPN_239 | MPN_329 | Conserved hypothetical protein; MPN239(new), 593(Himmelreich et al., 1996). | Ferric uptake regulator; MPN329(new), 508(Himmelreich et al., 1996); Koonin for MG homolog. | 0.615 |
K04_orf222 | whiA | MPN_239 | MPN_241 | Conserved hypothetical protein; MPN239(new), 593(Himmelreich et al., 1996). | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.910 |
K04_orf222 | ylxM | MPN_239 | MPN_424 | Conserved hypothetical protein; MPN239(new), 593(Himmelreich et al., 1996). | Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein (By similarity). | 0.693 |
ffh | ftsY | MPN_061 | MPN_425 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.999 |
ffh | smc | MPN_061 | MPN_426 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | SMC family, chromosome/DNA binding/protecting functions; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.402 |
ffh | ylxM | MPN_061 | MPN_424 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein (By similarity). | 0.683 |
ftsY | A05_orf129 | MPN_425 | MPN_423 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Conserved hypothetical protein; MPN423(new), 417(Himmelreich et al., 1996). | 0.779 |
ftsY | ffh | MPN_425 | MPN_061 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.999 |
ftsY | glpQ | MPN_425 | MPN_420 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Glycerophosphoryl diester phosphodiesterase; MPN420(new), 420(Himmelreich et al., 1996); To glycerophosphoryl diester phosphodiesterases (EC 3.1.4.46). | 0.497 |
ftsY | mnmA | MPN_425 | MPN_422 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.821 |
ftsY | smc | MPN_425 | MPN_426 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | SMC family, chromosome/DNA binding/protecting functions; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.924 |