CCL21 protein (Homo sapiens) - STRING network view

STRING 9.05

CCL21 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	CCL21	chemokine (C-C motif) ligand 21; Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs (134 aa)
		(Homo sapiens)
Predicted Functional Partners:
	CCR7	chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of E [...] (378 aa)	•	•	•	0.999
	CXCL13	chemokine (C-X-C motif) ligand 13; Chemotactic for B-lymphocytes but not for T-lymphocytes, mon [...] (109 aa)	•	•	•	0.990
	CCR5	chemokine (C-C motif) receptor 5; Receptor for a number of inflammatory CC-chemokines including [...] (352 aa)		•	•	0.973
	CXCR5	chemokine (C-X-C motif) receptor 5; Cytokine receptor that binds to B-lymphocyte chemoattractan [...] (372 aa)		•	•	0.973
	CCR6	chemokine (C-C motif) receptor 6; Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC [...] (374 aa)		•	•	0.964
	CXCL9	chemokine (C-X-C motif) ligand 9; Cytokine that affects the growth, movement, or activation sta [...] (125 aa)		•	•	0.963
	CXCL10	chemokine (C-X-C motif) ligand 10; Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 (98 aa)		•	•	0.963
	CXCL11	chemokine (C-X-C motif) ligand 11; Chemotactic for interleukin-activated T-cells but not unstim [...] (94 aa)		•	•	0.958
	CCR1	chemokine (C-C motif) receptor 1; Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP- [...] (355 aa)		•	•	0.958
	CCL27	chemokine (C-C motif) ligand 27; Chemotactic factor that attracts skin-associated memory T-lymp [...] (112 aa)		•	•	0.953

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Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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