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vht1 vht1 bio2 bio2 cut6 cut6 mug160 mug160 vac7 vac7 SPBC83.16c SPBC83.16c rpl2002 rpl2002 SPAC24H6.11c SPAC24H6.11c abc3 abc3 spe1 spe1 SPAC3G6.05 SPAC3G6.05
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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vht1Vitamin H transporter 1; Involved in uptake of biotin and desthiobiotin with the concomitant entry of protons; Belongs to the major facilitator superfamily. Allantoate permease family. (568 aa)    
Predicted Functional Partners:
bio2
Biotin synthase; Belongs to the radical SAM superfamily. Biotin synthase family.
   
  
 0.842
cut6
Acetyl-CoA carboxylase; Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
   
  
 0.762
mug160
Meiotically up-regulated gene 160 protein.
      
 0.753
vac7
Vacuolar segregation protein 7; Component of the PI(3,5)P2 regulatory complex that regulates both the synthesis and turnover of phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2). Directly involved in vacuolar membrane scission. Required for normal vacuole acidification, inheritance and morphology (By similarity).
   
  
 0.726
SPBC83.16c
Inclusion body clearance protein IML2; Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
      
 0.722
rpl2002
60S ribosomal protein L20-B.
      
 0.700
SPAC24H6.11c
Uncharacterized protein C24H6.11c.
   
  
 0.581
abc3
ATP-binding cassette transporter abc3; Iron-regulated vacuolar ABC-type transporter which may be responsible for mobilizing stored iron from the vacuole to the cytosol in response to iron deficiency.
   
 
 0.480
spe1
Ornithine decarboxylase; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
   
 
 0.480
SPAC3G6.05
Protein sym1.
   
  
 0.476
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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