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AURKA - Aurora kinase A; Mitotic serine/threonine kinase that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis. Required for initial activation of CDK1 at centrosomes. Phosphorylates numerous target proteins, including ARHGEF2, BORA, BRCA1, CDC25B, DLGP5, HDAC6, KIF2A, LATS2, NDE [...]
[a.k.a. ARK1, STK15, STK6,
TA14790 - Chr2.cand.401 - camp-dependent protein kinase, beta-catalytic subunit
[a.k.a. XP_951989.1, InterPro:IPR000961, GOA:Q4UF82,
TA11795 - Serine/threonine kinase, putative; Serine/threonine kinase; Belongs to the protein kinase superfamily
[a.k.a. XP_952530.1, Serine/threonine kinase, putative, UniProtKB/TrEMBL:Q4UDP1,
© STRING Consortium 2018
SIB - Swiss Institute of Bioinformatics
CPR - NNF Center for Protein Research
EMBL - European Molecular Biology Laboratory
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