node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A0G2K1K4_RAT | B2m | ENSRNOP00000071878 | ENSRNOP00000023017 | Ig-like domain-containing protein. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | 0.487 |
A0A0G2K1K4_RAT | Mr1 | ENSRNOP00000071878 | ENSRNOP00000004694 | Ig-like domain-containing protein. | Major histocompatibility complex class I-related gene protein; Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T- cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent (By similarity). | 0.755 |
B2m | A0A0G2K1K4_RAT | ENSRNOP00000023017 | ENSRNOP00000071878 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | Ig-like domain-containing protein. | 0.487 |
B2m | Cd74 | ENSRNOP00000023017 | ENSRNOP00000025354 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | 0.801 |
B2m | Cd8a | ENSRNOP00000023017 | ENSRNOP00000009516 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | T-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Sr [...] | 0.989 |
B2m | Mr1 | ENSRNOP00000023017 | ENSRNOP00000004694 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | Major histocompatibility complex class I-related gene protein; Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T- cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent (By similarity). | 0.820 |
B2m | RT1-A | ENSRNOP00000023017 | ENSRNOP00000071804 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | RT1 class Ia, locus A1; Belongs to the MHC class I family. | 0.997 |
B2m | RT1-A2 | ENSRNOP00000023017 | ENSRNOP00000050701 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | RT1 class I histocompatibility antigen, AA alpha chain; Involved in the presentation of foreign antigens to the immune system. | 0.998 |
B2m | RT1-DOa | ENSRNOP00000023017 | ENSRNOP00000034452 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | RT1 class II, locus DOa; Belongs to the MHC class II family. | 0.590 |
B2m | RT1-Da | ENSRNOP00000023017 | ENSRNOP00000048774 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | Histocompatibility 2, class II antigen E alpha; Belongs to the MHC class II family. | 0.686 |
B2m | RT1-S3 | ENSRNOP00000023017 | ENSRNOP00000001036 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | RT1 class Ib, locus S3; Belongs to the MHC class I family. | 0.999 |
Cd74 | B2m | ENSRNOP00000025354 | ENSRNOP00000023017 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | 0.801 |
Cd74 | Cd8a | ENSRNOP00000025354 | ENSRNOP00000009516 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | T-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Sr [...] | 0.416 |
Cd74 | Mr1 | ENSRNOP00000025354 | ENSRNOP00000004694 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | Major histocompatibility complex class I-related gene protein; Antigen-presenting molecule specialized in presenting microbial vitamin B metabolites. Involved in the development and expansion of a small population of T-cells expressing an invariant T- cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT lymphocytes are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent (By similarity). | 0.623 |
Cd74 | RT1-A | ENSRNOP00000025354 | ENSRNOP00000071804 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | RT1 class Ia, locus A1; Belongs to the MHC class I family. | 0.798 |
Cd74 | RT1-A2 | ENSRNOP00000025354 | ENSRNOP00000050701 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | RT1 class I histocompatibility antigen, AA alpha chain; Involved in the presentation of foreign antigens to the immune system. | 0.796 |
Cd74 | RT1-DOa | ENSRNOP00000025354 | ENSRNOP00000034452 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | RT1 class II, locus DOa; Belongs to the MHC class II family. | 0.914 |
Cd74 | RT1-Da | ENSRNOP00000025354 | ENSRNOP00000048774 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | Histocompatibility 2, class II antigen E alpha; Belongs to the MHC class II family. | 0.993 |
Cd74 | RT1-S3 | ENSRNOP00000025354 | ENSRNOP00000001036 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | RT1 class Ib, locus S3; Belongs to the MHC class I family. | 0.790 |
Cd8a | B2m | ENSRNOP00000009516 | ENSRNOP00000023017 | T-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Sr [...] | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | 0.989 |