rtcA protein (Methanothermobacter thermautotrophicus)

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	rtcA	Probable RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps- (A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A; (C) a non catalytic nucleophilic attack by the adjacent 2'hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity) (337 aa)
		(Methanothermobacter thermautotrophicus)
Predicted Functional Partners:
	MTH_1597	UPF0027 protein MTH_1597 (488 aa)	•	•		•	0.881
	rpiA	Ribose-5-phosphate isomerase A (226 aa)			•	•	0.752
	MTH550	DNA-dependent DNA polymerase family X (550 aa)	•				0.751
	MTH_1914	UPF0425 pyridoxal phosphate-dependent protein MTH_1914 (377 aa)	•				0.677
	MTH1262	hypothetical protein (163 aa)	•				0.675
	rpoL	DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription [...] (85 aa)	•				0.667
	MTH_1598	UPF0211 protein MTH_1598 (140 aa)	•				0.663
	MTH1354	NADH oxidase (450 aa)	•				0.658
	nac	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribo [...] (117 aa)	•				0.656
	prs	Ribose-phosphate pyrophosphokinase (285 aa)	•				0.654

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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