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cysl-2 cysl-2 cth-1 cth-1 cth-2 cth-2 sqrd-1 sqrd-1 ahcy-1 ahcy-1 F26H9.5 F26H9.5 got-1.2 got-1.2 Y9C9A.16 Y9C9A.16 cdo-1 cdo-1 nkat-3 nkat-3 nkat-1 nkat-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cysl-2Bifunctional L-3-cyanoalanine synthase/cysteine synthase; Primarily catalyzes the formation of cyanoalanine and hydrogen sulfide from cysteine and hydrogen cyanide. Can also catalyze, although less efficiently, the formation of cyanoalanine and hydrogen sulfide from either S-sulfocysteine or O-acetylserine and hydrogen cyanide and the formation of cysteine from either S-sulfocysteine or O- acetylserine and hydrogen sulfide. By catalyzing the assimilation of cyanide produced by P.aeruginosa, mediates resistance to infection. Involved in fertility, growth and aging. Does not mediate surv [...] (337 aa)    
Predicted Functional Partners:
cth-1
CystaTHionine gamma lyase.
 
 0.990
cth-2
Putative cystathionine gamma-lyase 2; Belongs to the trans-sulfuration enzymes family.
 
 0.983
sqrd-1
Pyr_redox_2 domain-containing protein.
  
 
 0.971
ahcy-1
Adenosylhomocysteinase; Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.946
F26H9.5
Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 
 0.936
got-1.2
Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the central nervous system.
   
 0.930
Y9C9A.16
Pyr_redox_2 domain-containing protein.
    
 0.924
cdo-1
Cysteine dioxygenase 1; Belongs to the cysteine dioxygenase family.
   
 
 0.921
nkat-3
Aminotran_1_2 domain-containing protein.
  
 
 0.919
nkat-1
Aminotran_1_2 domain-containing protein.
  
 
 0.918
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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