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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
Hsd17b3
Estradiol 17-beta-dehydrogenase 3 (EC 1.1.1.64) (17-beta-HSD 3) (Testicular 17-beta-hydroxysteroid dehydrogenase); Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH (By similarity) (306 aa)
(Rattus norvegicus)
Predicted Functional Partners:
Cyp17a1
Cytochrome P450 17A1 (EC 1.14.99.9) (CYPXVII) (P450-C17) (P450c17) (Steroid 17-alpha-hydroxylas [...] (507 aa)
     •• 0.953
Srd5a2
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (EC 1.3.99.5) (Steroid 5- alpha-reductase 2) (SR type 2 [...] (254 aa)
     •• 0.905
Cyp11b2
Cytochrome P450 11B3, mitochondrial precursor (EC 1.14.15.4) (EC 1.14.15.5) (CYPXIB3) (P450-Ald [...] (500 aa)
     •• 0.901
Hsd3b6
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type IV (3- beta-HSD IV) [Includes- 3 [...] (373 aa)
     •• 0.901
Hsd3b5
3 beta-hydroxysteroid dehydrogenase type 5 (3 beta-hydroxysteroid dehydrogenase type V) (3-beta [...] (373 aa)
     •• 0.901
ENSRNOG00000006598
cytochrome P450, subfamily 11B, polypeptide 3 (500 aa)
     •• 0.901
Cyp2u1
Cytochrome P450 2U1 (EC 1.14.14.1); Catalyzes the hydroxylation of arachidonic acid, docosahexa [...] (530 aa)
     •  0.899
Ugt2b3
UDP-glucuronosyltransferase 2B3 precursor (EC 2.4.1.17) (UDPGT) (Testosterone, dihydrotestoster [...] (530 aa)
     •  0.899
Ugt2b
UDP-glucuronosyltransferase 2B2 precursor (EC 2.4.1.17) (UDPGT) (3- hydroxyandrogen specific) ( [...] (527 aa)
     •  0.899
Ugt1
UDP-glucuronosyltransferase 1-1 precursor (EC 2.4.1.17) (UDPGT) (UGT1*1) (UGT1-01) (UGT1.1) (UG [...] (535 aa)
     •  0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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or custom value: or custom limit:
additional (white) nodes         or: network depth