MAFK protein (Homo sapiens) - STRING network view

STRING 9.05

MAFK protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian); Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor (156 aa)
		(Homo sapiens)
Predicted Functional Partners:
	NFE2	nuclear factor (erythroid-derived 2), 45kDa; Required for activity at the locus control region [...] (373 aa)	•	•	•		0.971
	HBE1	hemoglobin, epsilon 1; The epsilon chain is a beta-type chain of early mammalian embryonic hemo [...] (147 aa)		•	•		0.907
	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2; Transcriptional regulator [...] (841 aa)	•		•		0.906
	NFE2L2	nuclear factor (erythroid-derived 2)-like 2; Transcription activator that binds to antioxidant [...] (605 aa)	•		•		0.906
	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian); Since they lack a putative tr [...] (162 aa)		•	•	•	0.902
	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian); Interacts with the upstream p [...] (164 aa)		•	•	•	0.902
	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1; Transcriptional regulator [...] (736 aa)	•		•		0.881
	NGF	nerve growth factor (beta polypeptide); Nerve growth factor is important for the development an [...] (241 aa)			•		0.812
	NFE2L3	nuclear factor (erythroid-derived 2)-like 3; Activates erythroid-specific, globin gene expressi [...] (694 aa)	•		•		0.723
	NFE2L1	nuclear factor (erythroid-derived 2)-like 1; Activates erythroid-specific, globin gene expressi [...] (772 aa)	•		•	•	0.664

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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