DYRK1A protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	DYRK1A	Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Protein kinase minibrain homolog) (MNBH) (HP86) (Dual specificity YAK1-related kinase) (hMNB); May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates (754 aa)
		(Homo sapiens)
Predicted Functional Partners:
	WDR68	WD repeat protein 68 (WD repeat protein An11 homolog) (341 aa)	•		•	0.973
	FOXO1A	Forkhead box protein O1A (Forkhead in rhabdomyosarcoma); Transcription factor (655 aa)	•		•	0.966
	CCNL2	Cyclin-L2 (Paneth cell-enhanced expression protein); Transcriptional regulator which participat [...] (520 aa)	•		•	0.963
	CREB1	cAMP response element-binding protein (CREB); This protein binds the cAMP response element (CRE [...] (341 aa)	•		•	0.956
	DSCR1	Calcipressin-1 (Down syndrome critical region protein 1) (Myocyte- enriched calcineurin-interac [...] (252 aa)			•	0.947
	JUN	Transcription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-jun) (V-jun avian sarco [...] (331 aa)		•	•	0.917
	TP53	Cellular tumor antigen p53 (Tumor suppressor p53) (Phosphoprotein p53) (Antigen NY-CO-13); Acts [...] (393 aa)		•	•	0.917
	ASPH	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-h [...] (759 aa)		•		0.899
	EDN1	Endothelin-1 precursor (Preproendothelin-1) (PPET1) [Contains- Endothelin-1 (ET-1); Big endothe [...] (212 aa)		•		0.899
	CDKN1A	Cyclin-dependent kinase inhibitor 1 (p21) (CDK-interacting protein 1) (Melanoma differentiation [...] (164 aa)		•		0.899

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Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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