AGR2 protein (Homo sapiens) - STRING network view

STRING 9.05

AGR2 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	AGR2	anterior gradient homolog 2 (Xenopus laevis); Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth (175 aa)
		(Homo sapiens)
Predicted Functional Partners:
	LYPD3	LY6/PLAUR domain containing 3; Supports cell migration. May be involved in urothelial cell-matr [...] (346 aa)		•	•		0.990
	MUC2	mucin 2, oligomeric mucus/gel-forming; Coats the epithelia of the intestines, airways, and othe [...] (2817 aa)		•	•		0.943
	DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1); Forms part of the dystrophin-associated [...] (895 aa)		•	•		0.859
	AREGB	amphiregulin B; Bifunctional growth-modulating glycoprotein. Inhibits growth of several human c [...] (252 aa)			•		0.833
	AREG	amphiregulin; Bifunctional growth-modulating glycoprotein. Inhibits growth of several human car [...] (252 aa)			•		0.833
	RUVBL2	RuvB-like 2 (E. coli); Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA h [...] (463 aa)			•		0.800
	AGR3	anterior gradient homolog 3 (Xenopus laevis) (166 aa)	•		•	•	0.756
	TFF1	trefoil factor 1; Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provi [...] (84 aa)	•		•		0.686
	TFF3	trefoil factor 3 (intestinal); Involved in the maintenance and repair of the intestinal mucosa. [...] (130 aa)	•		•		0.675
	FOXA1	forkhead box A1; Transcription activator for a number of liver genes such as AFP, albumin, tyro [...] (472 aa)	•		•		0.607

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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