STRINGSTRING
Hba-a2 Hba-a2 Hbb-bs Hbb-bs Hbb-bt Hbb-bt Hp Hp Hbb-bh2 Hbb-bh2 Hba-a1 Hba-a1 Hbb-bh1 Hbb-bh1 Rps12 Rps12 Hbb-y Hbb-y Rps14 Rps14 Rps9 Rps9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hba-a2Hemoglobin subunit alpha; Involved in oxygen transport from the lung to the various peripheral tissues; Belongs to the globin family. (142 aa)    
Predicted Functional Partners:
Hbb-bs
Hemoglobin subunit beta-1; Involved in oxygen transport from the lung to the various peripheral tissues.
  
0.998
Hbb-bt
Hemoglobin, beta adult t chain.
  
0.994
Hp
Haptoglobin alpha chain; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pat [...]
   
 0.971
Hbb-bh2
Predicted gene, EG436003; Belongs to the globin family.
  
0.964
Hba-a1
Hemoglobin alpha, adult chain 1.
  
 
0.907
Hbb-bh1
Hemoglobin subunit beta-H1; This is an embryonic beta-type chain.
  
0.856
Rps12
40S ribosomal protein S12.
    
 0.842
Hbb-y
Hemoglobin subunit epsilon-Y2; Hemoglobin epsilon chain is a beta-type chain found in early embryos; Belongs to the globin family.
   
0.837
Rps14
40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.
    
 0.823
Rps9
40S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family.
    
 0.821
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.