STRING 10 
  HLA-DRB1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
HLA-DRB1
major histocompatibility complex, class II, DR beta 1 (266 aa)
(Homo sapiens)
Predicted Functional Partners:
CD4
CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regul [...] (458 aa)
      0.950
CD80
CD80 molecule; Involved in the costimulatory signal essential for T- lymphocyte activation. T-c [...] (288 aa)
      0.933
ICAM1
intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein [...] (532 aa)
      0.921
IRF8
interferon regulatory factor 8; Specifically binds to the upstream regulatory region of type I [...] (426 aa)
     0.919
PDCD1
programmed cell death 1; Inhibitory cell surface receptor involved in the regulation of T-cell [...] (288 aa)
      0.917
VCAM1
vascular cell adhesion molecule 1; Important in cell-cell recognition. Appears to function in l [...] (739 aa)
      0.916
CD86
CD86 molecule; Receptor involved in the costimulatory signal essential for T-lymphocyte prolife [...] (329 aa)
      0.916
IFNG
interferon, gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamm [...] (166 aa)
      0.917
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain (296 aa)
     0.915
HLA-A
major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens [...] (365 aa)
     0.910
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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