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LCK - Tyrosine-protein kinase Lck; Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T- cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein [...]
[a.k.a. LCK proto-oncogene, Src family tyrosine kinase, 3AC8, Q573B4,
Porphyromonas gingivalis W83
umuC - UmuC protein; Similar to GB:X13529, GB:U07236, GB:M36881, GB:X14055, SP:
, PID:187034, PID:34289, PID:34295, PID:349702, PID:35780, PID:460966, PID:553522, PID:775208, and PID:825687; identified by sequence similarity; putative
[a.k.a. PG_1338, AAQ66405.1, AAQ66405]
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SIB - Swiss Institute of Bioinformatics
CPR - NNF Center for Protein Research
EMBL - European Molecular Biology Laboratory
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