version_number_image
 
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
gyrA
DNA gyrase A; DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (893 aa)
(Staphylococcus epidermidis 12228)
Predicted Functional Partners:
gyrB
Topoisomerase II subunit B; DNA gyrase negatively supercoils closed circular double- stranded D [...] (643 aa)
  0.999
parE
DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It has [...] (666 aa)
  0.999
recF
DNA replication and repair protein recF; The recF protein is involved in DNA metabolism; it is [...] (371 aa)
      0.937
dnaN
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible [...] (377 aa)
      0.767
dnaA
Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and r [...] (451 aa)
      0.713
rpoB
DNA-dependant RNA polymerase beta-subunit; DNA-dependent RNA polymerase catalyzes the transcrip [...] (1183 aa)
       0.650
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways o [...] (203 aa)
      0.629
serS
Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoac [...] (428 aa)
       0.623
cmk
Cytidylate kinase (215 aa)
       0.608
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the AT [...] (349 aa)
     0.597
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
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additional (white) nodes         or: network depth