ASAH2 - Neutral ceramidase (EC 3.5.1.23) (NCDase) (N-CDase) (Acylsphingosine deacylase 2) (N-acylsphingosine amidohydrolase 2) (BCDase) (LCDase) (hCD) [Contains: Neutral ceramidase soluble form]; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1 [...]

ENSG00000072444 - Putative neutral ceramidase C; May hydrolyze the sphingolipid ceramide into sphingosine and free fatty acid (By similarity)