STRINGSTRING
Reg1a Reg1a Prss1 Prss1 Sh3tc1 Sh3tc1 Cela3b Cela3b Pnliprp2 Pnliprp2 Cela2a Cela2a Extl3 Extl3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Reg1aLithostathine; Might act as an inhibitor of spontaneous calcium carbonate precipitation. (165 aa)    
Predicted Functional Partners:
Prss1
Anionic trypsin-1; Belongs to the peptidase S1 family.
   
 
 0.457
Sh3tc1
SH3 domain and tetratricopeptide repeats 1 (Predicted).
      
 0.434
Cela3b
Elastase 3B, pancreatic (Predicted), isoform CRA_b; Belongs to the peptidase S1 family.
   
 
 0.419
Pnliprp2
Pancreatic lipase-related protein 2; Lipase with broad substrate specificity. Can hydrolyze both phospholipids and galactolipids. Shows a preference for 1,2- didodecanoylphosphatidylethanolamine and 1,2- didodecanoylphosphatidylglycerol, and has low activity towards 1,2- didodecanoylphosphatidylcholine (in vitro). Belongs to the AB hydrolase superfamily. Lipase family.
   
 
 0.408
Cela2a
Chymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily.
   
 
 0.407
Extl3
Exostoses (Multiple)-like 3, isoform CRA_a; Belongs to the glycosyltransferase 47 family.
      
 0.402
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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