node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cipc | Prph | ENSMUSP00000038630 | ENSMUSP00000049303 | CLOCK-interacting pacemaker; Transcriptional repressor which may act as a negative- feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK. However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock. | Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family. | 0.451 |
Nefh | Nefl | ENSMUSP00000091061 | ENSMUSP00000022639 | Neurofilament heavy polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. | Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | 0.995 |
Nefh | Nefm | ENSMUSP00000091061 | ENSMUSP00000022638 | Neurofilament heavy polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. | Neurofilament medium polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | 0.952 |
Nefh | Prph | ENSMUSP00000091061 | ENSMUSP00000049303 | Neurofilament heavy polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. | Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family. | 0.905 |
Nefl | Nefh | ENSMUSP00000022639 | ENSMUSP00000091061 | Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | Neurofilament heavy polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. | 0.995 |
Nefl | Nefm | ENSMUSP00000022639 | ENSMUSP00000022638 | Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | Neurofilament medium polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | 0.996 |
Nefl | Prph | ENSMUSP00000022639 | ENSMUSP00000049303 | Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family. | 0.910 |
Nefm | Nefh | ENSMUSP00000022638 | ENSMUSP00000091061 | Neurofilament medium polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | Neurofilament heavy polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. | 0.952 |
Nefm | Nefl | ENSMUSP00000022638 | ENSMUSP00000022639 | Neurofilament medium polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | 0.996 |
Nefm | Prph | ENSMUSP00000022638 | ENSMUSP00000049303 | Neurofilament medium polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family. | 0.906 |
Prph | Cipc | ENSMUSP00000049303 | ENSMUSP00000038630 | Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family. | CLOCK-interacting pacemaker; Transcriptional repressor which may act as a negative- feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK. However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock. | 0.451 |
Prph | Nefh | ENSMUSP00000049303 | ENSMUSP00000091061 | Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family. | Neurofilament heavy polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that is not subserved by the two smaller NF proteins. | 0.905 |
Prph | Nefl | ENSMUSP00000049303 | ENSMUSP00000022639 | Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family. | Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | 0.910 |
Prph | Nefm | ENSMUSP00000049303 | ENSMUSP00000022638 | Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family. | Neurofilament medium polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. | 0.906 |
Prph | Prss33 | ENSMUSP00000049303 | ENSMUSP00000059491 | Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family. | Serine protease 33; Serine protease that has amidolytic activity, cleaving its substrates before Arg residues. | 0.519 |
Prss33 | Prph | ENSMUSP00000059491 | ENSMUSP00000049303 | Serine protease 33; Serine protease that has amidolytic activity, cleaving its substrates before Arg residues. | Peripherin; Class-III neuronal intermediate filament protein; Belongs to the intermediate filament family. | 0.519 |