STRINGSTRING
GLUL GLUL GLUD2 GLUD2 GLS2 GLS2 CPS1 CPS1 PPAT PPAT GAD1 GAD1 GFPT1 GFPT1 GFPT2 GFPT2 GAD2 GAD2 ALDH18A1 ALDH18A1 ALDH4A1 ALDH4A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GLULGlutamine synthetase; Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine. When expressed in liver, it may be involved in detoxifying intramitochondrially generated ammonia. Also acts as glutamate decarboxylase by catalyzing the production of 4- aminobutanoate (gamma-aminobutyric acid, GABA) in a pyridoxal phosphate-independent manner. (413 aa)    
Predicted Functional Partners:
GLUD2
Glutamate dehydrogenase 1, mitochondrial; Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (By similarity).
  
 
 0.985
GLS2
ANK_REP_REGION domain-containing protein.
    
 0.981
CPS1
Uncharacterized protein.
  
 
 0.960
PPAT
Amidophosphoribosyltransferase.
    
 0.960
GAD1
Glutamate decarboxylase 67.
  
 
 0.957
GFPT1
Uncharacterized protein.
  
 
 0.948
GFPT2
Glutamine-fructose-6-phosphate transaminase 2.
  
 
 0.948
GAD2
Glutamate decarboxylase 2.
  
 
 0.936
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
    
 0.930
ALDH4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.930
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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