STRINGSTRING
Adra1b Adra1b Gna13 Gna13 Gna12 Gna12 Adra1a Adra1a Gna15 Gna15 Adra1d Adra1d Gna14 Gna14 Gna11 Gna11 Gnaq Gnaq Edn1 Edn1 Edn3 Edn3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Adra1bAlpha-1B adrenergic receptor; This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes (By similarity); Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1B sub-subfamily. (515 aa)    
Predicted Functional Partners:
Gna13
Guanine nucleotide-binding protein subunit alpha-13.
    
 0.906
Gna12
Guanine nucleotide-binding protein subunit alpha-12.
    
 0.905
Adra1a
alpha-1A adrenergic receptor isoform X1.
  
 
 
0.900
Gna15
Guanine nucleotide-binding protein subunit alpha-15 isoform X1.
    
 0.887
Adra1d
alpha-1D adrenergic receptor.
    
0.874
Gna14
Guanine nucleotide-binding protein subunit alpha-14 isoform X1.
    
 0.851
Gna11
Guanine nucleotide-binding protein subunit alpha-11.
    
 0.849
Gnaq
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.849
Edn1
Endothelin-1.
    
 0.822
Edn3
Endothelin-3.
    
 0.815
Your Current Organism:
Mesocricetus auratus
NCBI taxonomy Id: 10036
Other names: Golden hamsters, M. auratus, Syrian golden hamster, Syrian golden hamsters, Syrian hamster, Syrian hamsters, golden hamster
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