IL12B protein (Homo sapiens) - STRING network view

STRING 9.05

IL12B protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC (328 aa)
		(Homo sapiens)
Predicted Functional Partners:
	IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation fact [...] (253 aa)		•	•	•	0.999
	IL23A	interleukin 23, alpha subunit p19; Associates with IL12B to form the IL-23 interleukin, an hete [...] (189 aa)		•	•	•	0.998
	IL12RB1	interleukin 12 receptor, beta 1; Functions as an interleukin receptor which binds interleukin-1 [...] (381 aa)		•	•	•	0.993
	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; NF-kappa-B is a pleiotrop [...] (969 aa)			•	•	0.981
	IL12RB2	interleukin 12 receptor, beta 2; Receptor for interleukin-12. This subunit is the signaling com [...] (862 aa)		•	•	•	0.979
	IFNG	interferon, gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamm [...] (166 aa)			•	•	0.971
	IL6	interleukin 6 (interferon, beta 2); Cytokine with a wide variety of biological functions. It is [...] (212 aa)	•		•	•	0.963
	IL23R	interleukin 23 receptor; Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL2 [...] (629 aa)			•	•	0.958
	CD4	CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regul [...] (458 aa)			•	•	0.949
	IL4	interleukin 4; Participates in at least several B-cell activation processes as well as of other [...] (153 aa)	•		•	•	0.943

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes

Server load: low (36%)

Permalink