STRING 10 
  IL12B protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40); Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine- activated killer cells, and stimulate the production of IFN-gamma by resting PBMC (328 aa)
(Homo sapiens)
Predicted Functional Partners:
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation fact [...] (253 aa)
     0.999
IL23A
interleukin 23, alpha subunit p19; Associates with IL12B to form the IL-23 interleukin, a heter [...] (189 aa)
     0.998
IL12RB1
interleukin 12 receptor, beta 1; Functions as an interleukin receptor which binds interleukin-1 [...] (662 aa)
     0.987
FOS
FBJ murine osteosarcoma viral oncogene homolog; Nuclear phosphoprotein which forms a tight but [...] (380 aa)
      0.980
NOS2
nitric oxide synthase 2, inducible (1153 aa)
      0.966
IL12RB2
interleukin 12 receptor, beta 2; Receptor for interleukin-12. This subunit is the signaling com [...] (862 aa)
     0.963
JUN
jun proto-oncogene; Transcription factor that recognizes and binds to the enhancer heptamer mot [...] (331 aa)
      0.962
IL1B
interleukin 1, beta; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation [...] (269 aa)
      0.959
IL6
interleukin 6 (interferon, beta 2); Cytokine with a wide variety of biological functions. It is [...] (212 aa)
      0.952
IL4
interleukin 4; Participates in at least several B-cell activation processes as well as of other [...] (153 aa)
      0.952
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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