Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
There are several matches for 'P40692'.
Please select one from the list below and press Continue to proceed.
<- Back
Continue ->
organism
protein
1)
Homo sapiens
MLH1 - DNA mismatch repair protein Mlh1; Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH3) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing t [...]
[a.k.a. U17843, MLH1-226, ENST00000673713,
P40692
]
2)
Pyronema omphalodes
PCON_04722 - Similar to DNA mismatch repair protein Mlh1 acc. no.
P40692
.
[a.k.a. U4L512_PYROM, U4L512]