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Id2 - DNA-binding protein inhibitor ID-2; Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the C [...]
[a.k.a. Id-2, Idb2, DNA-binding protein inhibitor ID-2,
Vibrio cholerae O1
VC_1696 - DNA-binding protein inhibitor Id-2-related protein; Similar to SP:
PID:1030074; identified by sequence similarity; putative
[a.k.a. AAF94846.1, Q9KRE6, vcz:VAB027_2342]
© STRING Consortium 2019
SIB - Swiss Institute of Bioinformatics
CPR - NNF Center for Protein Research
EMBL - European Molecular Biology Laboratory
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