STRING 9.1 
  STAT5B protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
STAT5B
signal transducer and activator of transcription 5B; Carries out a dual function- signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription (787 aa)
(Homo sapiens)
Predicted Functional Partners:
JAK2
Janus kinase 2; Plays a role in leptin signaling and control of body weight (By similarity). Ty [...] (1132 aa)
     0.999
EGFR
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avi [...] (1210 aa)
     0.995
JAK1
Janus kinase 1; Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma [...] (1154 aa)
     0.995
JAK3
Janus kinase 3; Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and int [...] (1124 aa)
     0.993
INSR
insulin receptor; This receptor binds insulin and has a tyrosine-protein kinase activity. Isofo [...] (1382 aa)
      0.980
GHR
growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating pos [...] (638 aa)
      0.978
PRLR
prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin (PRL). Isof [...] (622 aa)
      0.977
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)
      0.962
PRL
prolactin; Prolactin acts primarily on the mammary gland by promoting lactation (227 aa)
       0.946
CREBBP
CREB binding protein; Acetylates histones, giving a specific tag for transcriptional activation [...] (2442 aa)
     0.935
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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