NAF1 protein (Saccharomyces cerevisiae)

STRING 9.05

NAF1 protein (Saccharomyces cerevisiae) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	NAF1	Uncharacterized protein YNL124W; RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disapears during maturation of the complex and is replaced by GAR1 to yield mature H/ACA snoRNPs complex. Acts as a competitive binder for CBF5 probably required to prevent non-cognate RNAs from being loaded during transport of the particle by inducing a non- productive conformation of CBF5 (By similarity) (492 aa)
		(Saccharomyces cerevisiae)
Predicted Functional Partners:
	CBF5	H/ACA ribonucleoprotein complex subunit 4 (EC 5.4.99.-) (Centromere/microtubule-binding protein [...] (483 aa)	•	•	•	0.999
	NHP2	H/ACA ribonucleoprotein complex subunit 2 (H/ACA snoRNP protein NHP2) (High mobility group-like [...] (156 aa)	•	•	•	0.999
	CBC2	Nuclear cap-binding protein subunit 2; Component of the CBC complex, which binds co- transcript [...] (208 aa)		•		0.998
	NAM8	Protein NAM8; Acts as a suppressor of mitochondrial splicing deficiencies when overexpressed. C [...] (523 aa)		•		0.998
	NOP10	H/ACA ribonucleoprotein complex subunit 3 (Nucleolar protein family A member 3) (snoRNP protein [...] (58 aa)		•		0.999
	MUD1	U1 small nuclear ribonucleoprotein A (U1 snRNP protein A) (U1-A); Involved in nuclear mRNA spli [...] (298 aa)		•		0.998
	GAR1	H/ACA ribonucleoprotein complex subunit 1 (snoRNP protein GAR1); Required for ribosome biogenes [...] (205 aa)	•	•	•	0.996
	SHQ1	Protein SHQ1 (Small nucleolar RNAs of the box H/ACA family quantitative accumulation protein 1) [...] (507 aa)	•	•	•	0.994
	NOP58	Nucleolar protein NOP58 (Nucleolar protein NOP5); Required for pre-18S rRNA processing. May bin [...] (511 aa)	•	•	•	0.919
	ERB1	Eukaryotic ribosome biogenesis protein 1; Component of the NOP7 complex, which is required for [...] (807 aa)	•	•		0.902

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