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NPEPPS - Puromycin-sensitive aminopeptidase; Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain; Aminopeptidases
[a.k.a. LOC101060212, LOC101929950, PSA,
MXAN_6822 - Aminopeptidase; Identified by similarity to SP:
[a.k.a. ABF92543.1, Q1CXD4, 108467358]
© STRING Consortium 2020
SIB - Swiss Institute of Bioinformatics
CPR - Novo Nordisk Foundation Center Protein Research
EMBL - European Molecular Biology Laboratory
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