HDAC2 protein (Gallus gallus) - STRING interaction network

HDAC2 protein (Gallus gallus) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	HDAC2	Histone deacetylase 2 (HD2); Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) (488 aa)
		(Gallus gallus)
Predicted Functional Partners:
	HDAC4	Histone deacetylase 4 (HD4); Responsible for the deacetylation of lysine residues on the N-term [...] (1071 aa)	•	•	•	•	•	0.936
	HDAC1	Histone deacetylase 1 (HD1); Responsible for the deacetylation of lysine residues on the N-term [...] (480 aa)	•	•	•	•	•	0.919
	HDAC3	Histone deacetylase 3 (HD3); Responsible for the deacetylation of lysine residues on the N-term [...] (428 aa)	•	•	•	•	•	0.918
	PFM1	PR domain zinc finger protein 4 (PR domain-containing protein 4) (804 aa)			•			0.899
	SIN3A	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase [...] (1269 aa)		•	•	•		0.748
	SMRT	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormon [...] (2447 aa)		•	•	•		0.684
	HIRA	Protein HIRA (TUP1-like enhancer of split protein 1) (cHIRA); Cooperates with ASF1A to promote [...] (1023 aa)				•		0.678
	ENSGALG00000002803	hypothetical protein LOC429060 (697 aa)		•	•	•		0.655
	RBBP4	Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-bindi [...] (425 aa)		•	•	•		0.648
	RBBP7	Histone-binding protein RBBP7 (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-bindi [...] (424 aa)		•	•	•		0.638

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth

Server load: low (21%)

Link to this page