version_number_image
 
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components- pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity) (370 aa)
(Staphylococcus aureus Mu50)
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes [...] (325 aa)
••• ••• 0.999
E25
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The [...] (430 aa)
• • ••• 0.997
bfmBAB
Branched-chain alpha-keto acid dehydrogenase E1 (327 aa)
••• ••• 0.996
pdhD
Dihydrolipoamide acetyltransferase E3 subunit; Lipoamide dehydrogenase is a component of the al [...] (468 aa)
• •  •• 0.996
SAV1518
dihydrolipoamide dehydrogenase (473 aa)
•    •• 0.973
pyk
Pyruvate kinase (585 aa)
•    •  0.917
ldhB
L-lactate dehydrogenase 2; Contributes to S.aureus growth during nitrosative stress in both aer [...] (319 aa)
     •• 0.909
ldhA
L-lactate dehydrogenase 1; Appears to be the primary factor that allows S.aureus growth during [...] (317 aa)
     •• 0.907
pycA
Pyruvate carboxylase (1150 aa)
•    •• 0.906
SAV2559
Putative D-specific D-2-hydroxyacid dehydrogenase (332 aa)
     •  0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes         or: network depth