STRINGSTRING
Tpt1 Tpt1 Eef1g Eef1g Uba52 Uba52 Rps3a Rps3a Rps6 Rps6 Rpl11 Rpl11 Rps24 Rps24 Rps8 Rps8 Rps12 Rps12 Rpl18 Rpl18 Eef1b2 Eef1b2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tpt1Translationally-controlled tumor protein; Involved in calcium binding and microtubule stabilization. (172 aa)    
Predicted Functional Partners:
Eef1g
Elongation factor 1-gamma; Probably plays a role in anchoring the complex to other cellular components.
   
 
 0.968
Uba52
Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]
   
   0.929
Rps3a
40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3.
   
 
 0.922
Rps6
Ribosomal protein S6.
   
 
 0.920
Rpl11
60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
   
   0.919
Rps24
40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family.
   
 
 0.902
Rps8
40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.
   
 
 0.899
Rps12
40S ribosomal protein S12.
   
 
 0.890
Rpl18
60S ribosomal protein L18; Component of the large ribosomal subunit.
   
 
 0.887
Eef1b2
Eukaryotic translation elongation factor 1 beta 2; Belongs to the EF-1-beta/EF-1-delta family.
  
 
 0.886
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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