node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SCM58533.1 | pcn | MWSIV6_1694 | MWSIV6_1701 | Putative protein MJ0043; sp|Q60348|Y043_METJA;evalue=4e-073; PctID=51.52; score=275. | DNA polymerase sliding clamp {ECO:0000255|HAMAP-Rule:MF_00317}; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.597 |
SCM58533.1 | pcrA1 | MWSIV6_1694 | MWSIV6_0854 | Putative protein MJ0043; sp|Q60348|Y043_METJA;evalue=4e-073; PctID=51.52; score=275. | Essential helicase; sp|Q5HN29|PCRA_STAEQ,sp|Q8CRT9|PCRA_STAES;evalue=4e-045; PctID=32.06; score=184. | 0.895 |
SCM58533.1 | pcrA3 | MWSIV6_1694 | MWSIV6_0882 | Putative protein MJ0043; sp|Q60348|Y043_METJA;evalue=4e-073; PctID=51.52; score=275. | ATP-dependent DNA helicase PcrA; Essential helicase. May act as a helicase in plasmid pT181 replication. Sequence=AAA72091.1; Type=Frameshift; Positions=666; Evidence=; sp|P64318|PCRA_STAAM,sp|P64319|PCRA_STAAN, sp|Q53727|PCRA_STAA8,sp|Q5HEL7|PCRA_STAAC, sp|Q6G828|PCRA_STAAS,sp|Q6GFF2|PCRA_STAAR, sp|Q8NVT1|PCRA_STAAW;evalue=2e-055; PctID=28.23; score=218. | 0.909 |
SCM58709.1 | pcn | MWSIV6_1794 | MWSIV6_1701 | Putative ATP-dependent RNA helicase MJ1505; sp|Q58900|Y1505_METJA;evalue=9e-098; PctID=39.93; score=358. | DNA polymerase sliding clamp {ECO:0000255|HAMAP-Rule:MF_00317}; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.828 |
SCM58709.1 | pcrA1 | MWSIV6_1794 | MWSIV6_0854 | Putative ATP-dependent RNA helicase MJ1505; sp|Q58900|Y1505_METJA;evalue=9e-098; PctID=39.93; score=358. | Essential helicase; sp|Q5HN29|PCRA_STAEQ,sp|Q8CRT9|PCRA_STAES;evalue=4e-045; PctID=32.06; score=184. | 0.827 |
SCM58709.1 | pcrA3 | MWSIV6_1794 | MWSIV6_0882 | Putative ATP-dependent RNA helicase MJ1505; sp|Q58900|Y1505_METJA;evalue=9e-098; PctID=39.93; score=358. | ATP-dependent DNA helicase PcrA; Essential helicase. May act as a helicase in plasmid pT181 replication. Sequence=AAA72091.1; Type=Frameshift; Positions=666; Evidence=; sp|P64318|PCRA_STAAM,sp|P64319|PCRA_STAAN, sp|Q53727|PCRA_STAA8,sp|Q5HEL7|PCRA_STAAC, sp|Q6G828|PCRA_STAAS,sp|Q6GFF2|PCRA_STAAR, sp|Q8NVT1|PCRA_STAAW;evalue=2e-055; PctID=28.23; score=218. | 0.827 |
SCM58709.1 | radA | MWSIV6_1794 | MWSIV6_1764 | Putative ATP-dependent RNA helicase MJ1505; sp|Q58900|Y1505_METJA;evalue=9e-098; PctID=39.93; score=358. | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.798 |
SCM58709.1 | radB | MWSIV6_1794 | MWSIV6_0230 | Putative ATP-dependent RNA helicase MJ1505; sp|Q58900|Y1505_METJA;evalue=9e-098; PctID=39.93; score=358. | DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. | 0.769 |
SCM58709.1 | topA | MWSIV6_1794 | MWSIV6_0170 | Putative ATP-dependent RNA helicase MJ1505; sp|Q58900|Y1505_METJA;evalue=9e-098; PctID=39.93; score=358. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.883 |
SCM58709.1 | uvrC | MWSIV6_1794 | MWSIV6_0825 | Putative ATP-dependent RNA helicase MJ1505; sp|Q58900|Y1505_METJA;evalue=9e-098; PctID=39.93; score=358. | UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203}; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.670 |
mre11 | pcn | MWSIV6_0906 | MWSIV6_1701 | DNA double-strand break repair protein Mre11 {ECO:0000255|HAMAP-Rule:MF_02044}; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | DNA polymerase sliding clamp {ECO:0000255|HAMAP-Rule:MF_00317}; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | 0.763 |
mre11 | pcrA1 | MWSIV6_0906 | MWSIV6_0854 | DNA double-strand break repair protein Mre11 {ECO:0000255|HAMAP-Rule:MF_02044}; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | Essential helicase; sp|Q5HN29|PCRA_STAEQ,sp|Q8CRT9|PCRA_STAES;evalue=4e-045; PctID=32.06; score=184. | 0.875 |
mre11 | pcrA3 | MWSIV6_0906 | MWSIV6_0882 | DNA double-strand break repair protein Mre11 {ECO:0000255|HAMAP-Rule:MF_02044}; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | ATP-dependent DNA helicase PcrA; Essential helicase. May act as a helicase in plasmid pT181 replication. Sequence=AAA72091.1; Type=Frameshift; Positions=666; Evidence=; sp|P64318|PCRA_STAAM,sp|P64319|PCRA_STAAN, sp|Q53727|PCRA_STAA8,sp|Q5HEL7|PCRA_STAAC, sp|Q6G828|PCRA_STAAS,sp|Q6GFF2|PCRA_STAAR, sp|Q8NVT1|PCRA_STAAW;evalue=2e-055; PctID=28.23; score=218. | 0.856 |
mre11 | radA | MWSIV6_0906 | MWSIV6_1764 | DNA double-strand break repair protein Mre11 {ECO:0000255|HAMAP-Rule:MF_02044}; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.929 |
mre11 | radB | MWSIV6_0906 | MWSIV6_0230 | DNA double-strand break repair protein Mre11 {ECO:0000255|HAMAP-Rule:MF_02044}; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. | 0.923 |
mre11 | topA | MWSIV6_0906 | MWSIV6_0170 | DNA double-strand break repair protein Mre11 {ECO:0000255|HAMAP-Rule:MF_02044}; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.932 |
mre11 | uvrB | MWSIV6_0906 | MWSIV6_0826 | DNA double-strand break repair protein Mre11 {ECO:0000255|HAMAP-Rule:MF_02044}; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | UvrABC system protein B {ECO:0000255|HAMAP-Rule:MF_00204}; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is foun [...] | 0.673 |
mre11 | uvrC | MWSIV6_0906 | MWSIV6_0825 | DNA double-strand break repair protein Mre11 {ECO:0000255|HAMAP-Rule:MF_02044}; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203}; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.700 |
pcn | SCM58533.1 | MWSIV6_1701 | MWSIV6_1694 | DNA polymerase sliding clamp {ECO:0000255|HAMAP-Rule:MF_00317}; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | Putative protein MJ0043; sp|Q60348|Y043_METJA;evalue=4e-073; PctID=51.52; score=275. | 0.597 |
pcn | SCM58709.1 | MWSIV6_1701 | MWSIV6_1794 | DNA polymerase sliding clamp {ECO:0000255|HAMAP-Rule:MF_00317}; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family. | Putative ATP-dependent RNA helicase MJ1505; sp|Q58900|Y1505_METJA;evalue=9e-098; PctID=39.93; score=358. | 0.828 |