version_number_image
 
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
E25
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components- pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (430 aa)
(Staphylococcus aureus N315)
Predicted Functional Partners:
pdhD
Dihydrolipoamide acetyltransferase E3 subunit; Lipoamide dehydrogenase is a component of the al [...] (468 aa)
••• ••• 0.999
pdhA
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes [...] (370 aa)
• • ••• 0.997
pdhB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes [...] (325 aa)
••• ••• 0.997
SA1349
dihydrolipoamide dehydrogenase (473 aa)
••• ••• 0.991
bfmBAA
Branched-chain alpha-keto acid dehydrogenase E1 (330 aa)
• •  •• 0.986
acsA
acetyl-coenzyme A synthetase (568 aa)
•    •  0.933
pta
Phosphate actyltransferase (Phosphate acetyltransferase) (328 aa)
•    •  0.929
bfmBAB
Branched-chain alpha-keto acid dehydrogenase E1 (327 aa)
••• ••• 0.926
odhA
2-oxoglutarate dehydrogenase E1 component; The 2-oxoglutarate dehydrogenase complex catalyzes t [...] (910 aa)
•• •••• 0.912
SA2402
Acetate-CoA ligase (539 aa)
•    •  0.908
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth