STRINGSTRING
IDUA IDUA ASL ASL NAGLU NAGLU IDS IDS ARSG ARSG ARSA ARSA GALNS GALNS ARSB ARSB HGSNAT HGSNAT SGSH SGSH SUMF1 SUMF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IDUAAlpha-L-iduronidase. (739 aa)    
Predicted Functional Partners:
ASL
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
   
  
 0.834
NAGLU
N-acetyl-alpha-glucosaminidase.
   
  
 0.800
IDS
Iduronate 2-sulfatase.
      
 0.800
ARSG
Arylsulfatase G; Displays arylsulfatase activity with pseudosubstrates at acidic pH, such as p-nitrocatechol sulfate.
   
  
 0.768
ARSA
Arylsulfatase A.
   
  
 0.719
GALNS
N-acetylgalactosamine-6-sulfatase.
   
  
 0.719
ARSB
Arylsulfatase B.
   
  
 0.707
HGSNAT
Heparan-alpha-glucosaminide N-acetyltransferase.
      
 0.615
SGSH
N-sulfoglucosamine sulfohydrolase.
   
  
 0.605
SUMF1
Sulfatase modifying factor 1.
   
 
 0.598
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.