aceK protein (Pseudomonas aeruginosa PA14) - STRING interaction network

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	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (577 aa)
		(Pseudomonas aeruginosa PA14)
Predicted Functional Partners:
	PA4400	Putative pyrophosphohydrolase (315 aa)			•		0.899
	cobT	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis [...] (351 aa)			•		0.899
	mtlZ	Fructokinase (310 aa)			•		0.899
	orfK	putative UDP-N-acetylglucosamine 2-epimerase (378 aa)			•		0.899
	thiE	Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophos [...] (209 aa)			•		0.899
	thiL	Thiamine monophosphate kinase (322 aa)			•		0.899
	ribH	6,7-dimethyl-8-ribityllumazine synthase; Riboflavin synthase is a bifunctional enzyme complex c [...] (158 aa)			•		0.899
	ribC	Riboflavin synthase alpha chain (219 aa)			•		0.899
	icd	Isocitrate dehydrogenase [NADP] (418 aa)	•	•		•	0.689
	PA1377	Putative uncharacterized protein (177 aa)	•				0.640

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Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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