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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) (329 aa)
(Lactococcus lactis SK11)
Predicted Functional Partners:
LACR_1583
GMP synthase (Glutamine-hydrolyzing) (513 aa)
   0.992
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotid [...] (430 aa)
    0.974
purH
Bifunctional purine biosynthesis protein purH (518 aa)
       0.966
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of A [...] (170 aa)
      0.949
LACR_0225
Inosine-5'-monophosphate dehydrogenase (493 aa)
   0.927
LACR_2158
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (205 aa)
      0.913
LACR_1606
Hypoxanthine-guanine phosphoribosyltransferase (180 aa)
       0.899
LACR_1194
5'-nucleotidase/2',3'-cyclic phosphodiesterase related esterase (255 aa)
       0.899
LACR_0017
Hypoxanthine-guanine phosphoribosyltransferase (183 aa)
       0.899
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic [...] (197 aa)
      0.594
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes         or: network depth