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TAP1 - Antigen peptide transporter 1; Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation [...]
[a.k.a. RING4, Y3, ABCB2,
Pseudomonas syringae tomato
PSPTO_3053 - Porin; Similar to GB:X57522, GB:U07197, GB:U07198, GB:X57521, GB:L21204, GB:L21205, GB:L21206, GB:L21207, GB:L21208, GB:S70256, GB:S70266, GB:S70274, GB:S70260, SP:
, PID:1054745, PID:34636, PID:36061, PID:463921, and PID:930122; identified by sequence similarity; putative
[a.k.a. AAO56542.1, WP_011104353.1, conserved domain protein]
© STRING Consortium 2019
SIB - Swiss Institute of Bioinformatics
CPR - NNF Center for Protein Research
EMBL - European Molecular Biology Laboratory
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