TPP1 protein (Saccharomyces cerevisiae) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

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DNA 3'-phosphatase that functions in repair of endogenous damage of double-stranded DNA, activity is specific for removal of 3' phosphates at strand breaks; has similarity to the l-2-haloacid dehalogenase superfamily; Dephosphorylate DNA's 3'-phosphate termini. Has a role in the repair of breaks in single stranded DNA (238 aa)
(Saccharomyces cerevisiae)
Predicted Functional Partners:
Class II abasic (AP) endonuclease involved in repair of DNA damage; homolog of human HAP1 and E [...] (520 aa)
Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage [...] (367 aa)
Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA during nucleotide e [...] (1100 aa)
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, s [...] (602 aa)
DNA 5' AMP hydrolase involved in DNA repair; member of the histidine triad (HIT) superfamily of [...] (217 aa)
Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3' and 5'-phosphotyrosyl bonds, involved in the rep [...] (544 aa)
Putative kinase with similarity to the phosphoribulokinase/uridine kinase/bacterial pantothenat [...] (353 aa)
DNA polymerase IV, undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repa [...] (582 aa)
Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cycloh [...] (799 aa)
Protein of unknown function; null mutant displays reduced respiratory growth and elevated frequ [...] (255 aa)
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