node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C16orf96 | SLC38A11 | ENSP00000415027 | ENSP00000386272 | Uncharacterized protein C16orf96; Chromosome 16 open reading frame 96. | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | 0.553 |
C16orf96 | ZNF142 | ENSP00000415027 | ENSP00000398798 | Uncharacterized protein C16orf96; Chromosome 16 open reading frame 96. | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.634 |
COBLL1 | SLC38A11 | ENSP00000487041 | ENSP00000386272 | Cordon-bleu WH2 repeat protein like 1. | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | 0.440 |
GJD4 | SLC38A11 | ENSP00000315070 | ENSP00000386272 | Gap junction delta-4 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell; Belongs to the connexin family. Delta-type subfamily. | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | 0.401 |
MAP3K7 | SLC38A11 | ENSP00000358335 | ENSP00000386272 | Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | 0.569 |
REELD1 | SLC38A11 | ENSP00000490412 | ENSP00000386272 | Reelin domain-containing protein 1; Reeler domain containing 1. | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | 0.594 |
SLC38A11 | C16orf96 | ENSP00000386272 | ENSP00000415027 | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | Uncharacterized protein C16orf96; Chromosome 16 open reading frame 96. | 0.553 |
SLC38A11 | COBLL1 | ENSP00000386272 | ENSP00000487041 | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | Cordon-bleu WH2 repeat protein like 1. | 0.440 |
SLC38A11 | GJD4 | ENSP00000386272 | ENSP00000315070 | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | Gap junction delta-4 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell; Belongs to the connexin family. Delta-type subfamily. | 0.401 |
SLC38A11 | MAP3K7 | ENSP00000386272 | ENSP00000358335 | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | Mitogen-activated protein kinase kinase kinase 7; Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as a [...] | 0.569 |
SLC38A11 | REELD1 | ENSP00000386272 | ENSP00000490412 | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | Reelin domain-containing protein 1; Reeler domain containing 1. | 0.594 |
SLC38A11 | SLC38A9 | ENSP00000386272 | ENSP00000380074 | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | 0.560 |
SLC38A11 | SLC43A2 | ENSP00000386272 | ENSP00000461382 | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | Large neutral amino acids transporter small subunit 4; Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids. | 0.432 |
SLC38A11 | SLC7A4 | ENSP00000386272 | ENSP00000372390 | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | Cationic amino acid transporter 4; Involved in the transport of the cationic amino acids (arginine, lysine and ornithine); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. | 0.465 |
SLC38A11 | ZNF142 | ENSP00000386272 | ENSP00000398798 | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.459 |
SLC38A9 | SLC38A11 | ENSP00000380074 | ENSP00000386272 | Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...] | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | 0.560 |
SLC43A2 | SLC38A11 | ENSP00000461382 | ENSP00000386272 | Large neutral amino acids transporter small subunit 4; Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids. | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | 0.432 |
SLC43A2 | SLC7A4 | ENSP00000461382 | ENSP00000372390 | Large neutral amino acids transporter small subunit 4; Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids. | Cationic amino acid transporter 4; Involved in the transport of the cationic amino acids (arginine, lysine and ornithine); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. | 0.528 |
SLC7A4 | SLC38A11 | ENSP00000372390 | ENSP00000386272 | Cationic amino acid transporter 4; Involved in the transport of the cationic amino acids (arginine, lysine and ornithine); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. | Putative sodium-coupled neutral amino acid transporter 11; Putative sodium-dependent amino acid/proton antiporter. | 0.465 |
SLC7A4 | SLC43A2 | ENSP00000372390 | ENSP00000461382 | Cationic amino acid transporter 4; Involved in the transport of the cationic amino acids (arginine, lysine and ornithine); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family. | Large neutral amino acids transporter small subunit 4; Sodium-, chloride-, and pH-independent high affinity transport of large neutral amino acids. | 0.528 |