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rcl1 rcl1 enp1 enp1 bms1 bms1 utp20 utp20 rrp9 rrp9 utp24 utp24 nop14 nop14 pwp2 pwp2 lcp5 lcp5 mpp10 mpp10 utp21 utp21
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
rcl1Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. (363 aa)    
Predicted Functional Partners:
enp1
Uncharacterized protein C13G1.09; Belongs to the bystin family.
   
 
 0.999
bms1
Ribosome biogenesis protein bms1; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. BMS1 subfamily.
   
 0.999
utp20
U3 small nucleolar RNA-associated protein 20; Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
 
 0.998
rrp9
Uncharacterized WD repeat-containing protein C2E1P5.05.
   
 
 0.997
utp24
rRNA-processing protein fcf1; Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly. Required for the early cleavage steps of 35S rRNA at the A(0), A(1), and A(2) sites (By similarity). Belongs to the UTP23/FCF1 family. FCF1 subfamily.
   
 
 0.996
nop14
Probable nucleolar complex protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
   
 
 0.996
pwp2
Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family.
   
 
 0.996
lcp5
Uncharacterized protein C18B11.06.
   
 
 0.995
mpp10
U3 small nucleolar ribonucleoprotein protein mpp10; Component of the U3 small nucleolar ribonucleoprotein. Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing (By similarity).
   
 
 0.994
utp21
U3 small nucleolar RNA-associated protein 21 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
 
 0.994
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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