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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
aceK
Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (622 aa)
(Burkholderia ambifaria)
Predicted Functional Partners:
Bamb_2080
Isocitrate lyase (435 aa)
•  •  • 0.794
Bamb_2084
malate synthase A (530 aa)
•     • 0.713
Bamb_2572
isocitrate dehydrogenase, NADP-dependent (418 aa)
• •   • 0.681
Bamb_2976
Carbonate dehydratase (256 aa)
•       0.631
Bamb_2974
Beta-lactamase domain protein (384 aa)
•       0.567
Bamb_1291
protein of unknown function DUF1228 (408 aa)
  •     0.553
Bamb_1861
Bacteriophage-acquired protein (253 aa)
  •     0.531
Bamb_0792
protein of unknown function UPF0153 (105 aa)
  •     0.473
Bamb_6331
Transcriptional regulator, AraC family (397 aa)
  •     0.467
Bamb_2571
Isocitrate dehydrogenase, NADP-dependent (742 aa)
•       0.432
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:
additional (white) nodes         or: network depth