version_number_image
 
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
aceK
Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (574 aa)
(Escherichia coli 536)
Predicted Functional Partners:
thiE
Thiamin phosphate synthase (Thiamin phosphate pyrophosphorylase); Condenses 4-methyl-5-(beta-hy [...] (211 aa)
       0.899
rffE
UDP-N-acetylglucosamine 2-epimerase (376 aa)
       0.899
xylA
Xylose isomerase (440 aa)
       0.899
nanA
N-acetylneuraminate lyase; Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to f [...] (297 aa)
       0.899
nanE
Putative N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate [...] (229 aa)
       0.899
scrK
Fructokinase (306 aa)
       0.899
cscK
Fructokinase (305 aa)
       0.899
cobT
Nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase; Catalyzes the synthesi [...] (359 aa)
       0.899
ribC
Riboflavin synthase, alpha subunit (213 aa)
       0.899
thiL
Thiamine-monophosphate kinase (325 aa)
       0.899
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes         or: network depth