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This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) (347 aa)
(Escherichia coli 536)
Predicted Functional Partners:
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotid [...] (432 aa)
• •  •• 0.982
guaA
GMP synthetase (Glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP (525 aa)
•  • •• 0.979
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of A [...] (183 aa)
     •• 0.951
gsk
Inosine/guanosine kinase (434 aa)
     •• 0.939
guaB
Inosine-5'-monophosphate dehydrogenase (511 aa)
  •• •••0.937
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (By similarity) (207 aa)
     •• 0.936
hpt
Hypoxanthine phosphoribosyltransferase (143 aa)
     •• 0.903
yjjG
Putative uncharacterized protein (225 aa)
     •  0.899
purH
purine biosynthesis protein PurH (529 aa)
     •  0.899
ECP_4154
putative 5'-nucleotidase/2',3'-cyclic phosphodiesterase or related esterase (517 aa)
     •  0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.
Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes         or: network depth