AKT2 protein (Homo sapiens) - STRING interaction network

AKT2 protein (Homo sapiens) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




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Your Input:
	AKT2	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta); General protein kinase capable of phosphorylating several known proteins (481 aa)
		(Homo sapiens)
Predicted Functional Partners:
	SLC2A4	Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, [...] (509 aa)		•	•	•		0.998
	INS	Insulin precursor [Contains- Insulin B chain; Insulin A chain]; Insulin decreases blood glucose [...] (110 aa)			•	•		0.994
	TCL1A	T-cell leukemia/lymphoma protein 1A (P14 TCL1 protein) (TCL1 oncogene) (TCL-1 protein); Enhance [...] (114 aa)		•		•		0.989
	TBC1D4	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160); May act as a GTPase-activating [...] (1299 aa)			•	•		0.982
	GSK3B	Glycogen synthase kinase-3 beta (EC 2.7.11.26) (GSK-3 beta); Participates in the Wnt signaling [...] (433 aa)		•	•	•	•	0.971
	TSC2	Tuberin (Tuberous sclerosis 2 protein); Implicated as a tumor suppressor. May have a function i [...] (1807 aa)		•	•	•		0.971
	TRIB3	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (p65-interacting inh [...] (358 aa)		•	•	•	•	0.968
	PDPK1	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (hPDK1); Phosphorylates and activat [...] (556 aa)	•	•	•	•	•	0.968
	PIK3CA	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (EC 2.7.1.153) ( [...] (1069 aa)			•	•		0.967
	AKT1	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) [...] (480 aa)	•	•	•	•	•	0.960

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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