STRINGSTRING
SURF6 SURF6 EBNA1BP2 EBNA1BP2 NIFK NIFK MAK16 MAK16 RPF1 RPF1 PPAN PPAN GTPBP4 GTPBP4 BRIX1 BRIX1 RRP15 RRP15 GNL2 GNL2 MRTO4 MRTO4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
SURF6Surfeit locus protein 6; Binds to both DNA and RNA in vitro, with a stronger binding capacity for RNA. May represent a nucleolar constitutive protein involved in ribosomal biosynthesis or assembly (By similarity). Belongs to the SURF6 family. (353 aa)    
Predicted Functional Partners:
EBNA1BP2
EBNA1 binding protein 2.
   
 
 0.971
NIFK
MKI67 FHA domain-interacting nucleolar phosphoprotein.
   
 
 0.970
MAK16
Protein MAK16 homolog.
   
   0.966
RPF1
Ribosome production factor 1 homolog.
   
 
 0.957
PPAN
Brix domain-containing protein.
   
 
 0.957
GTPBP4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.953
BRIX1
Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
   
 
 0.953
RRP15
RRP15-like protein.
   
 
 0.947
GNL2
Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
   
 
 0.942
MRTO4
mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
   
  
 0.940
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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