proS protein (Alcanivorax borkumensis) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	proS	Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction- proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (566 aa)
		(Alcanivorax borkumensis)
Predicted Functional Partners:
	proC	Pyrroline-5-carboxylate reductase (269 aa)		•	0.899
	pip	proline iminopeptidase (PIP) (307 aa)		•	0.899
	dxr	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and [...] (404 aa)	•		0.799
	uppS	Undecaprenyl diphosphate synthase (260 aa)	•		0.798
	ispG	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclo [...] (372 aa)	•		0.796
	frr	Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the t [...] (185 aa)	•		0.796
	cdsA	Phosphatidate cytidylyltransferase (274 aa)	•		0.795
	pyrH	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) (252 aa)	•		0.795
	tsf	Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to [...] (313 aa)	•		0.793
	rpsB	30S ribosomal protein S2 (252 aa)	•		0.788

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth