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pex11 pex11 pex19 pex19 pex13 pex13 pex3 pex3 pex14 pex14 pex5 pex5 pex6 pex6 fis1 fis1 dnm1 dnm1 mdm34 mdm34 pts1 pts1
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pex11Peroxisomal biogenesis factor 11; Involved in peroxisomal proliferation. Promotes peroxisome division and biogenesis (By similarity); Belongs to the peroxin-11 family. (238 aa)    
Predicted Functional Partners:
pex19
Uncharacterized protein C17C9.14.
   
 0.991
pex13
Peroxisomal membrane protein pex13; Component of the peroxisomal translocation machinery with pex14 and pex17; Belongs to the peroxin-13 family.
   
 0.955
pex3
Uncharacterized protein C29A4.14c.
   
 0.954
pex14
Peroxisomal membrane protein pex14; Component of the peroxisomal translocation machinery with pex13 and pex17; Belongs to the peroxin-14 family.
    
 0.913
pex5
Peroxisomal targeting signal receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
   
 
 0.902
pex6
Peroxisomal ATPase pex6; Component of the peroxisomal protein import machinery. Together with pex1, mediates the ATP-dependent relocation and recycling of the peroxisomal targeting signal-1 (PTS1) import receptor PEX5 from the peroxisomal membrane to the cytosol, where it is then available for another round of protein import into the organelle (By similarity). Belongs to the AAA ATPase family.
    
 
 0.899
fis1
Mitochondrial fission 1 protein; Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity).
   
 0.855
dnm1
Dynamin-related protein dnm1; Microtubule-associated force-producing protein that mediates mitochondrial fission during interphasic growth and at cell division. Fission of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. With vps1, acts redundantly in peroxisome biogenesis, which is under cell cycle control.
    
 
 0.838
mdm34
Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.
    
 
 0.829
pts1
Probable proteasome subunit beta type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity; Belongs to the peptidase T1B family.
   
  
 0.762
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 284812
Other names: S. pombe 972h-, Schizosaccharomyces pombe 972h-
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