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F46H5.3 F46H5.3 F38B2.4 F38B2.4 ant-1.1 ant-1.1 mlc-3 mlc-3 unc-15 unc-15 aldo-2 aldo-2 tpi-1 tpi-1 mlc-6 mlc-6 mlc-7 mlc-7 alh-8 alh-8 mlc-5 mlc-5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
F46H5.3Probable arginine kinase F46H5.3; Belongs to the ATP:guanido phosphotransferase family. (396 aa)    
Predicted Functional Partners:
F38B2.4
Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
   
 
 0.667
ant-1.1
Adenine Nucleotide Translocator; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
 
 0.665
mlc-3
Myosin, essential light chain.
   
 
 0.615
unc-15
Paramyosin; Structural component of the muscle thick filaments which is involved in assembly and organization of sarcomere myofilaments. Involved in ovulation. Plays a role in the formation of muscle connections, also called muscle arm extensions, between the body wall and the motor axons in the dorsal and ventral cord. Belongs to the paramyosin family.
   
 
 0.608
aldo-2
Fructose-bisphosphate aldolase 2.
   
 
 0.584
tpi-1
Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.
   
 
 0.580
mlc-6
Myosin Light Chain.
   
 
 0.574
mlc-7
Myosin Light Chain.
   
 
 0.574
alh-8
Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA (By similarity); Belongs to the aldehyde dehydrogenase family.
   
 
 0.572
mlc-5
Myosin-2 essential light chain; Required for cytokinesis and embryo elongation. May regulate myosin II complex formation and/or the association of myosin with actin. May be involved in the organization of mlc-4 and nmy-2 into bundles.
   
 
 0.557
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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