node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BET1 | GOS1 | YIL004C | YHL031C | Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; Belongs to the BET1 family. | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | 0.999 |
BET1 | NYV1 | YIL004C | YLR093C | Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; Belongs to the BET1 family. | v-SNARE component of the vacuolar SNARE complex; involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane. | 0.999 |
BET1 | PEP12 | YIL004C | YOR036W | Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; Belongs to the BET1 family. | Syntaxin PEP12; Target membrane receptor (t-SNARE); for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin. | 0.833 |
BET1 | SEC17 | YIL004C | YBL050W | Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; Belongs to the BET1 family. | Alpha-soluble NSF attachment protein; Alpha-SNAP cochaperone; SNARE-complex adaptor for Sec18 (NSF) during the disassembly of postfusion cis-SNARE complexes; stimulates the ATPase activity of Sec18p; peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, and autophagy; similar to mammalian alpha-SNAP. | 0.981 |
BET1 | SED5 | YIL004C | YLR026C | Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; Belongs to the BET1 family. | Integral membrane protein SED5; cis-Golgi t-SNARE syntaxin; required for vesicular transport between the ER and the Golgi complex; binds at least 9 SNARE proteins. | 0.999 |
BET1 | TLG1 | YIL004C | YDR468C | Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; Belongs to the BET1 family. | Essential t-SNARE that mediates fusion of vesicles with the late Golgi; forms a complex with Tlg2p and Vti1p; mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p; Belongs to the syntaxin family. | 0.943 |
BET1 | VAM7 | YIL004C | YGL212W | Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; Belongs to the BET1 family. | Vacuolar SNARE protein; functions with Vam3p in vacuolar protein trafficking; has an N-terminal PX domain (phosphoinositide-binding module) that binds PtdIns-3-P and mediates membrane binding; SNAP-25 homolog; protein abundance increases in response to DNA replication stress. | 0.916 |
BET1 | VTI1 | YIL004C | YMR197C | Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; Belongs to the BET1 family. | t-SNARE VTI1; Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and Pep12p; required for multiple vacuolar sorting pathways; human homolog VTI1A can complement yeast null mutant; Belongs to the VTI1 family. | 0.979 |
GOS1 | BET1 | YHL031C | YIL004C | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; Belongs to the BET1 family. | 0.999 |
GOS1 | NYV1 | YHL031C | YLR093C | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | v-SNARE component of the vacuolar SNARE complex; involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane. | 0.999 |
GOS1 | PEP12 | YHL031C | YOR036W | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | Syntaxin PEP12; Target membrane receptor (t-SNARE); for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin. | 0.999 |
GOS1 | SEC17 | YHL031C | YBL050W | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | Alpha-soluble NSF attachment protein; Alpha-SNAP cochaperone; SNARE-complex adaptor for Sec18 (NSF) during the disassembly of postfusion cis-SNARE complexes; stimulates the ATPase activity of Sec18p; peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, and autophagy; similar to mammalian alpha-SNAP. | 0.939 |
GOS1 | SED5 | YHL031C | YLR026C | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | Integral membrane protein SED5; cis-Golgi t-SNARE syntaxin; required for vesicular transport between the ER and the Golgi complex; binds at least 9 SNARE proteins. | 0.999 |
GOS1 | TLG1 | YHL031C | YDR468C | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | Essential t-SNARE that mediates fusion of vesicles with the late Golgi; forms a complex with Tlg2p and Vti1p; mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p; Belongs to the syntaxin family. | 0.989 |
GOS1 | VAM7 | YHL031C | YGL212W | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | Vacuolar SNARE protein; functions with Vam3p in vacuolar protein trafficking; has an N-terminal PX domain (phosphoinositide-binding module) that binds PtdIns-3-P and mediates membrane binding; SNAP-25 homolog; protein abundance increases in response to DNA replication stress. | 0.944 |
GOS1 | VPS33 | YHL031C | YLR396C | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | Vacuolar protein sorting-associated protein 33; ATP-binding protein that is a subunit of the HOPS and CORVET complexes; essential for protein sorting, vesicle docking, and fusion at the vacuole; binds to SNARE domains. | 0.410 |
GOS1 | VTI1 | YHL031C | YMR197C | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | t-SNARE VTI1; Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and Pep12p; required for multiple vacuolar sorting pathways; human homolog VTI1A can complement yeast null mutant; Belongs to the VTI1 family. | 0.989 |
NYV1 | BET1 | YLR093C | YIL004C | v-SNARE component of the vacuolar SNARE complex; involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane. | Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins; Belongs to the BET1 family. | 0.999 |
NYV1 | GOS1 | YLR093C | YHL031C | v-SNARE component of the vacuolar SNARE complex; involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane. | Golgi SNAP receptor complex member 1; v-SNARE protein involved in Golgi transport; homolog of the mammalian protein GOS-28/GS28. | 0.999 |
NYV1 | PEP12 | YLR093C | YOR036W | v-SNARE component of the vacuolar SNARE complex; involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane. | Syntaxin PEP12; Target membrane receptor (t-SNARE); for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin. | 0.999 |