rtcA protein (Methanococcoides burtonii) - STRING interaction network

This is the evidence view. Different line colors represent the types of evidence for the association.




confidence	evidence	actions	interactive	advanced	more	less	save

Your Input:
	rtcA	Probable RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps- (A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A; (C) a non catalytic nucleophilic attack by the adjacent 2'hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity) (331 aa)
		(Methanococcoides burtonii)
Predicted Functional Partners:
	Mbur_1767	FAD-dependent pyridine nucleotide-disulphide oxidoreductase (453 aa)	•		0.869
	Mbur_2207	protein of unknown function UPF0027 (486 aa)	•	•	0.838
	Mbur_0773	Ribose-5-phosphate isomerase (231 aa)		•	0.752
	rpoL	DNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription [...] (91 aa)	•		0.671
	Mbur_1877	Ribose-phosphate pyrophosphokinase (282 aa)	•		0.655
	Mbur_2208	protein of unknown function DUF101 (146 aa)	•		0.654
	Mbur_1786	Nascent polypeptide associated complex NAC (116 aa)	•		0.651
	Mbur_1807	Putative uncharacterized protein (159 aa)	•		0.640
	Mbur_1438	RNA binding protein (237 aa)	•		0.636
	Mbur_1437	methyltransferase small (203 aa)	•		0.632

Views:

Info & Parameters ...

Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

required confidence (score):

interactors shown:

or custom value:

or custom limit:

additional (white) nodes		or: network depth