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TP53BP2 - Apoptosis-stimulating of p53 protein 2; Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42; Belongs to the ASPP family
[a.k.a. ASPP2, BBP, OTTHUMP00000216701,
TA06815 - Uncharacterized protein; Tap349e08.q2ks7.C.cand.97 - score = 21.22
[a.k.a. XP_954032.1, Q4UHT4, GOA:Q4UHT4,
TA20480 - Contains several Ankyrin repeat elements
[a.k.a. XP_954255.1, GeneID:3863507, InterPro:IPR011990,
© STRING Consortium 2018
SIB - Swiss Institute of Bioinformatics
CPR - NNF Center for Protein Research
EMBL - European Molecular Biology Laboratory
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