aceK protein (Rhodopseudomonas palustris BisB5)

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Your Input:
	aceK	Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity) (606 aa)
		(Rhodopseudomonas palustris BisB5)
Predicted Functional Partners:
	RPD_0376	Transcriptional modulator of MazE/toxin, MazF (111 aa)	•		0.577
	RPD_0375	Putative uncharacterized protein (78 aa)	•		0.577
	RPA0346	protein of unknown function DUF540 (249 aa)	•		0.472
	RPD_3849	Outer membrane autotransporter barrel (684 aa)		•	0.400

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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:

Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining

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